Infertility

Unwanted childlessness is a growing problem with which up to 20% of all couples in reproductive age are confronted temporarily or long-term. Infertility may be caused by antibodies against various tissues and cells that are essential for reproduction. In 20% of cases of immunologically mediated fertility disorders, anti-spermatozoa antibodies are detected (autoantibodies in men or alloantibodies in women). These antibodies primarily impair the mobility of the spermatozoa through surface binding and through agglutination processes. 

The IIFT: Spermatozoa allows to detect serum antibodies against spermatozoa using indirect immunofluorescence.